84-3393-62　ASC (TMS1, Target of Methylation-induced Silencing) (CT) (FITC) 100ul　A3598-05H-FITC

特徴

• TMS1, also known as apoptosis-associated speck-like protein containing a CARD (ASC).
• It was first identified as a cytosolic soluble protein that forms insoluble aggregates and promotes caspase-mediated apoptosis.
• The proapoptotic activity is mediated predominantly though the activation of caspase 9.
• It may also be a component of the inflammasome, where it associates with caspase 1, CARD8 and NALP2 to activate proinflammatory caspases.
• TMS1 is widely expressed in human tissue
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/ml ~25kD in HL60 cell lysates
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.