84-3392-83　［取扱停止］Ring Finger Protein 34 (RNF34, Caspase Regulator CARP1, Caspases 8 and 10-associated RING Finger Protein 1, CARP-1, FLJ21786, FYVE-RING Finger Protein Momo, hRFI, Human RING Finger Homologous to Inhibitor of Apoptosis Protein hRFI, RFI, RIFF, Ring Finger Protein RIFF) (Biotin) 100ul　R2031-88B-Biotin

特徴

• Ring Finger is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL.
• It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation.
• hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm.
• hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:ELISA: 1:800-1:4000Western Blot: 1:100-1:600.
• Detects a band at ~42kDOptimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.