Human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), is a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway.
IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R.
Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).
Applications:Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence.
Other applications not tested.
Recommended Dilution:ELISA: 1:50,000Immunohistochemistry (Paraffin): 1:50Immunofluorescence: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Specificity：Recognizes an epitope within the N-terminal region of human Interleukin-22 Receptor.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa42-70, DSGPEGTPDTVYSIEYKTYGERDWVAKKG, within the N-terminal region of human IL-22 Receptor.
