84-3391-89　Interleukin 17 (IL-17, CTLA8, IL-17A, Interleukin-17A precursor, Cytotoxic T-lymphocyte-associated antigen 8) (Biotin) 100ul　I8439-07-Biotin

特徴

• Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) is a proinflammatory cytokine produced by activated T cells.
• This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases.
• This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).
• High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
• Interleukin-17 (IL-17) and its cognate receptor, IL- 17R, are examples of cytokine receptor pairs.
• IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function.
• Applications:Suitable for use in ELISA, Western Blot and Functional Assays.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.5-2ug/mlWestern Blot: 0.1-0.2ug/mlFunctional Assays: 0.93-1.3ug/mlOptimal working dilutions to be determined by researcher.
• Matched Pair:Detection: I8439-04R: Interleukin 17 (Biotin)Capture: I8439-07: Interleukin 17
• Recommended Secondary Antibodies:I1903-30U IgG, H&L, X-adsorbed (HRP)I1904-40J: IgG, Fc (HRP) Pab Gt xRbI1904-40P: IgG, Fc, X-Adsorbed (HRP) Pab Gt xRb
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.
• Note: Applications are based on unconjugated antibody.