84-3391-87　Interleukin 15 (IL-15) (Biotin) 100ul　I8437-01X-Biotin

特徴

• (Interleukin-15) is a 14kDa immunomodulatory glycoprotein expressed by multiple tissues and cell types, which primarily stimulates T lymphocytes, but is also critical for the development and activation of natural killer cells (NK).
• IL-15 shares functional properties with IL-2 and binds with high affinity to the IL-15 receptor (IL-15R), consisting of the IL-15R alpha chain, and also the IL-2Rbeta and common gamma chains used by the IL-2 receptor.
• Affects of IL-15 have been linked with cells and tissues unrelated to the immune system, and increased expression of IL-15 has been demonstrated in Rheumatoid Arthritis (RA), ulcerative colitis (UC) Chron’s disease (CD) and lymphoid malignancies, and also conditions affiliated with HIV and HTLV-1 infection.
• Applications:Suitable for use in ELISA, Western Blot, Neutralization, Immunohistochemistry and Immunoprecipitation.
• Other applications have not been tested.
• Recommended Dilution:Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining paraffin sections.
• Sodium citrate buffer, pH 6.0 is recommended
• Optimal working dilutions to be determined by researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.