ADAM-17, which is also known as CD156b, is expressed in a wide range of cells in culture.
Its biological role is to convert the transmembrane trimeric form of TNF alpha to the soluble form.
CD156 is also reported to process a number of other proteins, including L-selectin and TNF p75 receptor.
Applications:Suitable for use in Western Blot.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:500Optimal dilutions to be determined by researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography from whole serum.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Specificity：Recognizes the C-terminal region of the TNF alpha converting enzyme (TACE), designated CD156b at the 6th leukocyte typing workshop. TACE is a membrane-bound metalloprotease disintegrin which belongs to the mammalian ADAM family.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Ma
Immunogen：Peptide corresponding to aa 807-823 of human CD156b
