WNV belongs to the Flaviviridae family which includes closely viruses such as Dengue fever, Yellow fever and Tick borne encephalitis.
West Nile Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope containing envelope and matrix proteins.
Research indicates that the viral core protein contributes to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway.
West Nile Virus is believed to have originated in the West Nile region of Africa and has now spread to Europe, Asia and America where it has become a significant disease affecting human and domestic animal health.
Applications:Suitable for use in ELISA, and Western Blot.
Other applications not tested.
Recommended Dilutions:ELISA: 1ug/ml20ug/mlWestern Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
Specificity：Recognizes the 14kD core protein of West Nile Virus (WNV).
Isotype：IgG
Calc Applications Abbrev：E WB
Immunogen：A peptide corresponding to a 15aa sequence from near the C-terminus of West Nile Virus core protein.
