84-3385-83　［取扱停止］PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3, PACSIN-3, Endophilin 1, Endophilin I, Endophilin-I, SH3 Domain-containing Protein 6511) (MaxLight 750) 100ul　P1793-10D-ML750

特徴

• MaxLight™750 is a new Near IR stable dye conjugate comparable to DyLight™750, Alexa Fluor™700 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (759nm); Emission (780nm); Extinction Coefficient 240,000.
• A member of the Endophilin family, Endophilin A1 is a protein containing SH3 domains, and has been implicated in the trafficking of clathrin-mediated synaptic vesicle endocytosis within the membrane.
• It was originally characterized as a presynaptically enriched protein that binds to endocytic proteins polyphosphoinositide synaptojanin and dynamin.
• Endophilin A1 has been implicated in endocytic vesicle budding when its function in cell-free systems and in living synapses has been disturbed.
• Along with the SH3 domain, Endophilin A1 contains a BAR domain in the N-terminal region, that has been found to induce and bind membrane curvature.
• This protein’s expression is localized to the brain, most specifically in the frontal cortex.
• Markedly high expression is observed in fetal cerebellum.
• Applications: Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500Optimal dilutions to be determined by the researcher.
• Positive Control:Mouse brain tissue lysate.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™750 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.