84-3377-83　FOXH1 (Forkhead Box H1, Human Homolog of Xenopus Forkhead Activin Signal Transducer 1) (MaxLight 550) 100ul　F9047-20A-ML550

特徴

• MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000.
• Forkhead box H1 (FOXH1) is a member of the HNF–3FKH family of transcriptional activators.
• FOXH1 is a winged helix with two loops on the C-terminal side expressed in all human tissue.
• FOXH1 is an embryonic transcription regulator and is an essential transcriptional co-activator that binds with SMAD2 to activate activin, and therefore induce the gooseciod (GSC) promoter.
• After FOXH1 binds to SMAD4, activin response element is activated and TGF-β is stimulated.
• FOXH1 also interacts with NKX2-5 to form an essential component of anterior heart field development.
• FOXH1 is associated with complex brain malfunctions due to incomplete cleavage of the prosencephalon, and in developmental delays resulting in facial abnormalities such as cyclopia and severe cleft lip or palate.
• Applications:Suitable for use in Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Immunocytochemistry: 1:500Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™550 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.