MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
Forkhead box protein 1 (FOXP1) is a member of the Forkhead family of transcription factors, which have been characterized as transcriptional repressors and activators, and as having a DNA-binding domain distinguished by its formation of a winged-helix motif.
FOXP1 is known to be an important regulator of airway morphogenesis, lung epithelial development, and early cardiac development.
It is also known to have an important role in conjunction with NFκβ in the development of B-cells and the differentiation of macrophages.
Splice variants give rise to four isoforms of FOXP1.
The protein is known to form homodimers and heterodimers with FOXP2 and FOXP4.
Studies have indicated FOXP1 as a potential inducer of oncogenesis when over expressed.
The depletion and mutation of FOXP1 expression may lead to defects in embryonic cardiac, lung and esophagus epithelial development.
Applications: Suitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Positive Control:linear peptide corresponding to the C-terminus of human FOXP1.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™490 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Specificity：Recognizes the C-terminus of human FOXP1. Species Crossreactivity: rat and mouse
Isotype：IgG
Calc Applications Abbrev：IC IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Linear peptide corresponding to the C-terminus of human FOXP1 (KLH). Species sequence homology: bovine and rhesus macaque.
