FGFR-1 is a member of the basic fibroblast growth factor family of proteins and is thought to be important in the induction and propagation of benign prostatic hyperplasia.
A shortage of FGFR-1 causes death post-implantation and has been linked to neurofascin and neurite outgrowth.
FGFR-1 expression has recently been found to be increased in patients with renal cell carcinoma and FGFR-1 may also have a role to play in early limb formation.
Applications:Suitable for use in Western Blot and Cell Function Assay.
Other applications not tested.
Recommended Dilution:Western Blot: 0.2ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Untreated and lambda phosphatase-treated HEK293T cells transfected with FGFR-1
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity：Recognizes human FGFR-1 phosphorylated at Tyr653/Tyr654.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic linear peptide corresponding to human FGFR-1 phosphorylated at Tyr653/Tyr654 (KLH). Species sequence homology: mouse, rat, chicken, bovine, xenopus and zebrafish.
