Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation.
They are related to Drosophila atonal.
The neurogenins (ngns) make up one of these atonal-related gene families.
In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (Mash1 Is Essential for Noradrenergic Differentiation).
Neurogenin-3 promotes pancreatic development.
Applications:Suitable for use in Immunohistochemistry and Immunocytochemistry.
Not recommended for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Positive Control:Rat brain tissue
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish peroxidase (HRP).
Specificity：Recognizes mouse Neurogenin 3 at ~23kD. Species Crossreactivity: human and rat
Isotype：IgG
Calc Applications Abbrev：IC IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Linear peptide corresponding to aa80-93, QRRSRRKKANDRER of mouse Neurogenin 3
