Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals.
mTORC1 is activated in response to growth factors or amino-acids.
Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.
Applications:Suitable for use in Western Blot and Dot Blot
Other applications not tested.
Recommended Dilution:Dot Blot: detected Raptor in modified and non modified peptides of phosphorylated and non-phosphorylated Raptor protein.
Optimal dilutions to be determined by the researcher.
Positive Control:Modified and non modified peptides of phosphorylated and non-phosphorylated Raptor protein.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity：Recognizes human Raptor phosphorylated at Ser722.
Isotype：IgG
Calc Applications Abbrev：DB WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Ser722. Species Sequence homology: mouse, rat, canine, bovine, goat, chicken and equine.
