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84-3348-83 [取扱停止]RENT1 (Regulator of Nonsense Transcripts 1, ATP-dependent Helicase RENT1, Delta Helicase, FLJ43809, FLJ46894, hUPF1, KIAA0221, Nonsense mRNA Reducing Factor 1, NORF1, pNORF1, pNORF-1, UP Frameshift 1, UPF1, Up Frameshift Mutation 1 Homolog (S. cerevisiae), Up-frameshift Mutation 1 Homolog (S. cerevisiae), Up Frameshift Suppressor 1 Homolog, UPF1 Regulator of Nonsense Transcripts Homolog, Yeast ... R1495-03C-AP
84-3348-83 [取扱停止]RENT1 (Regulator of Nonsense Transcripts 1, ATP-dependent Helicase RENT1, Delta Helicase, FLJ43809, FLJ46894, hUPF1, KIAA0221, Nonsense mRNA Reducing Factor 1, NORF1, pNORF1, pNORF-1, UP Frameshift 1, UPF1, Up Frameshift Mutation 1 Homolog (S. cerevisiae), Up-frameshift Mutation 1 Homolog (S. cerevisiae), Up Frameshift Suppressor 1 Homolog, UPF1 Regulator of Nonsense Transcripts Homolog, Yeast ... R1495-03C-AP
特徴
- RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.
- mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).
- When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons.
- RENT1 is located only in the cytoplasm.
- When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Positive Control:U2OS cell lysate
- Storage and Stability:Store product at 4°C.
- DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Note: Applications are based on unconjugated antibody.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
- Specificity:Recognizes human RENT1.
- Isotype:IgG
- Calc Applications Abbrev:WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic linear peptide corresponding to RENT1. Species sequence homology: mouse, rat, bovine and canine.
- Shelf Life:1year
- Swiss Prot Number:Q92900
- EU Commodity Code:30021010
- 商品名:RENT1 (Regulator of Nonsense Transcripts 1, ATP-dependent Helicase RENT1, Delta Helicase, FLJ43809, FLJ46894, hUPF1, KIAA0221, Nonsense mRNA Reducing Factor 1, NORF1, pNORF1, pNORF-1, UP Frameshift 1, UPF1, Up Frameshift Mutation 1 Homolog (S. cerevisiae), Up-frameshift Mutation 1 Homolog (S. cerevisiae), Up Frameshift Suppressor 1 Homolog, UPF1 Regulator of Nonsense Transcripts Homolog, Yeast Upf1p Homolog) (AP) 100ul
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- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
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