MaxLight™750 is a new Near IR stable dye conjugate comparable to DyLight™750, Alexa Fluor™700 and offers better labeling efficiency, brighter imaging and increased immunodetection.
RBL2 is a key regulator of entry into cell division.
Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.
Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression.
Controls histone H4 'Lys-20' trimethylation.
Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.
Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5.
Binds to cyclins A and E.
Binds to and may be involved in the transforming capacity of the adenovirus E1A protein.
RBL2 may act as a tumor suppressor.
Applications:Suitable for use in Western Blot, Flow Cytometry (Not Tested), FLISA
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™750 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™750.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：FLISA WB
Calc Crossreactivity：Hu
Immunogen：RBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from the N-terminal region of human RBL2.
