MaxLight™750 is a new Near IR stable dye conjugate comparable to DyLight™750, Alexa Fluor™700 and offers better labeling efficiency, brighter imaging and increased immunodetection.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells.
The expression of this protein is inducible by TNF and IL-1 alpha.
This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6.
It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells.
This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.
[provided by RefSeq].
Applications:Suitable for use in FLISA, Western Blot and Immunofluorescence.
Other potential application, though not tested is Direct Flow Cytometry.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™750 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™750.
Specificity：Recognizes human TNFSF15.
Isotype：IgG
Calc Applications Abbrev：FLISA IF WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 148-175 in the central region of human TNFSF15.
