84-3208-76　［取扱停止］Dnmt3L (DNA (Cytosine-5)-methyltransferase 3-like) (MaxLight 750) 100ul　D3931-73M-ML750

特徴

• MaxLight™750 is a new Near IR stable dye conjugate comparable to DyLight™750, Alexa Fluor™700 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (759nm); Emission (780nm); Extinction Coefficient 240,000.
• mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues.
• It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci.
• It is required specifically for the establishment of genomic imprints but is dispensable for their propagation.
• It is essential for the de novo methylation of single-copy DNA sequences.
• The protein is well-express in testis, thymus, ovary, and heart.
• mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
• Applications:Suitable for use in FLISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:FLISA: 1:1,000 Western Blot: 1:100-1:500Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™750 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.