84-3090-01 [取扱停止]UHRF1, ID (E3 Ubiquitin-protein Ligase UHRF1, Ubiquitin-like PHD and RING Finger Domain-containing Protein 1, Ubiquitin-like-containing PHD and RING Finger Domains Protein 1, Inverted CCAAT box-binding Protein of 90kD, Transcription Factor ICBP90, Nuclear Zinc Finger Protein Np95, HuNp95, RING Finger Protein 106, Nuclear Protein 95, ICBP90, NP95, RNF106) (MaxLight 650) 100ul U1008-01-ML650
84-3090-01 [取扱停止]UHRF1, ID (E3 Ubiquitin-protein Ligase UHRF1, Ubiquitin-like PHD and RING Finger Domain-containing Protein 1, Ubiquitin-like-containing PHD and RING Finger Domains Protein 1, Inverted CCAAT box-binding Protein of 90kD, Transcription Factor ICBP90, Nuclear Zinc Finger Protein Np95, HuNp95, RING Finger Protein 106, Nuclear Protein 95, ICBP90, NP95, RNF106) (MaxLight 650) 100ul U1008-01-ML650
MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection.
UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases.
The protein binds to specific DNA sequences, and recruits a histone acetylase to regulate gene expression.
Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle.
It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.
Applications:Suitable for use in FLISA and Western Blot.
Other applications not tested.
Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™650 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Specificity:Recognizes human UHRF1.
Isotype:IgG
Calc Applications Abbrev:FLISA WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide selected from the Center region of human UHRF1 (KLH).