MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection.
TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family.
This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Applications:Suitable for use in FLISA and Dot Blot.
Other applications not tested.
Recommended Dilution:Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™650 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Specificity:Recognizes human TrkA phosphorylated at Tyr791.
Isotype:IgG
Calc Applications Abbrev:DB FLISA
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic phosphopeptide mapping to a fragment of residues surrounding Tyr791 of human TrkA, UniProt Accession #P04629