84-3076-73　［取扱停止］MEK1, phosphorylated (Ser217, Ser221) (MAPK/ERK Kinase 1, MEK 1, Dual Specificity Mitogen-Activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAP2K1, MAPKK 1, MKK1, PRKMK1, ERK Activator Kinase 1) (MaxLight 650) 100ul　M2865-12D-ML650

特徴

• MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000.
• MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family.
• This kinase is known to play a critical role in mitogen growth factor signal transduction.
• It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3.
• The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases.
• The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
• Applications:Suitable for use in FLISA, Western Blot, and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™650 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.