84-2999-70 [取扱停止]NR3C2, ID (NR3C2, MCR, MLR, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2) (MaxLight 550) 100ul 039130-ML550
84-2999-70 [取扱停止]NR3C2, ID (NR3C2, MCR, MLR, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2) (MaxLight 550) 100ul 039130-ML550
MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection.
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells.
The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes.
Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting.
Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy.
Alternative splicing results in multiple transcript variants.
Applications:Suitable for use in Western Blot and FLISA.
Other applications have not been tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™550 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Specificity:Recognizes human NR3C2.
Isotype:IgG
Calc Applications Abbrev:FLISA WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 654-683 in the central region of human NR3C2. Species Sequence Homology: mouse, rat and Xenopus