MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection.
Runx2 is a member of the RUNX family of transcription factors.
It is a nuclear protein with an Runt DNA-binding domain.
This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression.
It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex.
Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Applications:Suitable for use in FLISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:FLISA: 1:1,000Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™550 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Specificity:Recognizes human RUNX2.
Isotype:IgG
Calc Applications Abbrev:FLISA IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide selected from the N-terminal region of human RUNX2 (KLH).
Shelf Life:1year
Swiss Prot Number:Q13950
EU Commodity Code:30021010
商品名:RUNX2, NT (Runt-related Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 Enhancer Factor 1 alpha A Subunit, SL3/AKV Core-binding Factor alpha A Subunit, Osteoblast-specific Transcription Factor 2, OSF-2, AML3, CBFA1, OSF2, PEBP2A) (MaxLight 550) 100ul