84-2891-08　［取扱停止］IL5RA, NT (IL5RA, IL5R, Interleukin-5 receptor subunit alpha, CDw125, CD125) (MaxLight 490) 100ul　037015-ML490

特徴

• MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.
• IL5RA is an interleukin 5 specific subunit of a heterodimeric cytokine receptor.
• The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5).
• The binding of this protein to IL5 depends on the beta subunit.
• The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5.
• This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and FLISA.
• Other potential application, though not tested is Direct Flow Cytometry.
• Other applications have not been tested.
• Recommended Dilution:mmunohistochemistry: Formalin fixed paraffin embedded sections
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™490 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.