MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family.
Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation.
The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function.
Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells.
BBS proteins may also be involved in intracellular trafficking via microtubule-related transport.
The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins.
As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins.
Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.
Applications:Suitable for use in Western Blot, Flow Cytometry (Not Tested), FLISA
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™490 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：FLISA WB
Calc Crossreactivity：Hu
Immunogen：BBS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 520-550 from the C-terminal region of human BBS10.
