MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
MAP2 is the major microtubule associated protein of brain tissue.
There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c).
In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent.
Between postnatal days 10 and 20, MAP2a appears.
At the same time, the level of MAP2c drops by 10-fold.
This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology.
MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats.
There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types.
MAP2 is known to promote microtubule assembly and to form side-arms on microtubules.
It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™490 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：DB FLISA
Calc Crossreactivity：Hu
Immunogen：Phospho-MAP2-S1539 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 1524~1553 amino acids surrounding S1539 of human MAP2.
