MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
This gene is a member of the CLC family of voltage-gated chloride channels.
The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel.
It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear.
The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™490 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Specificity：Recognizes human CLCNKA at ~75kD.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa20-47 in the N-terminal region of human CLCNKA, UniProt Accession #P51800; NP_001036169.1; NP_004061.3 Cellular Location: Membrane; Multi-pass membrane protein. Tissue Location: Expressed predominantly in kidney.
