84-2822-85　［取扱停止］DLK (DLK1, DLK, Protein delta homolog 1, pG2, Fetal antigen 1) (MaxLight 490) 100ul　034665-ML490

特徴

• MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.
• This gene encodes a transmembrane protein containing six epidermal growth factor repeats.
• The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor.
• It is one of several imprinted genes located in a region of on chr 14q32.
• Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14).
• This gene is expressed from the paternal allele.
• A polymorphism within this gene has been associated with child and adolescent obesity.
• The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and FLISA.
• Other applications have not been tested.
• Recommended Dilution:Immunohistochemistry: Formalin-fixed, paraffin-embedded sectionsOptimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™490 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.