84-2802-42　［取扱停止］ADAMTS4, CT (ADMP-1, Aggrecanase-1, A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4, ADAMTS-4, ADAM-TS 4, ADAM-TS4, KIAA0688, UNQ769/PRO1563) (MaxLight 490) 100ul　A0859-60A-ML490

特徴

• MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.
• ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family.
• Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
• Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
• The enzyme lacks a C-terminal TS motif.
• It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein.
• The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
• Applications:Suitable for use in FLISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:FLISA: 1:1000Western Blot: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™490 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.