PGP9.5, Park5 or UCHL1, is a soluble cytoplasmic protein with a molecular weight of ~25kD.
It is present in neurons and in cells of the diffuse neuroendocrine system.
It is an excellent marker for neurons of the CNS and PNS.
The great abundance of this protein in neurons means that it is released from neurons in large amounts following injury or degeneration and is detected in CSF and other bodily fluids.
It is used as a bio-marker for Parkinson's Disease (PD), Alzheimer's Disease (AD), Axonal dystrophies and Traumatic Brain Injury (TBI).
Applications:Suitable for use in Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:500Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Serum
Purity:Serum
Form:Supplied as a liquid in 10mM sodium azide.
Specificity:Recognizes human UCHL1. Species Crossreactivity: rat, mouse, primate, bovine
Isotype:IgG
Calc Applications Abbrev:IF WB
Calc Crossreactivity:Bo Hu Mk Mo Rt
Immunogen:Full length recombinant protein corresponding to human UCHL1 expressed in E. coli.