Peripherin is a type III intermediate filament found initially in sensory neurons of the peripheral nervous system (PNS).
It serves as a marker for autonomic and sensory neurons in the PNS and motor neurons in the CNS.
Peripherin is a diagnostic marker in amyotrophic lateral sclerosis and certain neuronally-derived tumors.
Brain injuries can also trigger expression of peripherin and the formation of peripherin accumulations in neurons that are normally silent for this gene.
Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas.
Autoantibodies to peripherin are also frequently seen in the sera of patients with diabetes.
Applications:Suitable for use in Western Blot and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:20,000 Immunocytochemistry: 1:1000 (fluorescent secondary antibodies), 1:5000 (peroxidase) Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid.
Specificity：Recognizes Peripherin. Species Crossreactivity: human, rat, mouse, feline
Isotype：IgG
Calc Applications Abbrev：IC WB
Calc Crossreactivity：Fe Hu Mo Rt
Immunogen：Full length recombinant protein corresponding to peripherin, expressed in E. coli.
