84-2655-27　［取扱停止］Nuclear Receptor Subfamily 4, Group A, Member 2 (Nurr1, NOT, NURR1, TINUR, Nuclear Receptor of T Cells, Nuclear Receptor Related 1, Transcriptionally Inducible Nuclear Receptor) 100ul　299482

特徴

• The Nurr1 gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily.
• The encoded protein may act as a transcription factor.
• Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype.  In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000-1:2000Immunohistochemistry: 1:100-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.