MARCKS is a major protein of brain, and is concentrated in synapses of neurons.
It appears to function in synaptic vesicle cycling and has been shown to bind both actin and calmodulin in vitro.
MARCKS belongs to a family of proteins with similar actin and calmodulin binding properties.
Deletion of the MARCKS gene in mice results in embryonic brain defects and death. It plays a vital role in the normal developmental processes of neurulation, hemisphere fusion, forebrain commissure formation, and formation of cortical and retinal laminations.
Applications:Suitable for use in Immunofluorescence, Western Blot and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:500-1000Western Blot: 1:10,000-20,000Immunocytochemistry(ABC): 1:5000 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Serum
Purity：Serum
Form：Supplied as a liquid.
Specificity：Recognizes MARCKS. Species Crossreactivity: mouse, rat
Isotype：IgG
Calc Applications Abbrev：IC IF WB
Calc Crossreactivity：Mo Rt
Immunogen：Recombinant protein corresponding to MARCKS.
