GDNF, Neurturin, Artemin, and Persephin are distant members of the TGF-beta superfamily that function as neurotrophic factors.
Their bioactivities are mediated by a receptor complex composed of the non-ligand-binding signaling subunit (c-Ret receptor tyrosine kinase) and one of four ligand binding subunits designated GFR alpha-1 through 4, which are cysteine-rich glycosyl-phosphatidylinositol (GPI)-linked cell surface proteins.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-5ug/mlImmunohistochemistry(Paraffin): 5ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes mouse GFRa-3.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide corresponding to aa347-360 of mouse GFRa-3.
