The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP.
Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Paraffin): 1:2000-1:5000 Immunocytochemistry: 1:4000Western Blot: 1:3000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 20ul or 100ul sterile ddH2O.
Specificity：Recognizes human Relaxin Receptor 1. Does not react with human Relaxin Receptor 2. Species Crossreactivity: monkey (macaque, marmoset), mouse, porcine and rat.
Isotype：IgG
Calc Applications Abbrev：IC IHC WB
Calc Crossreactivity：Hu Mc Mk Mo Po Rt
Immunogen：Synthetic peptide corresponding to aa609-624, SAITATEIRNQVKKEM, of human Relaxin Receptor 1, KLH conjugated.
