84-2654-57 ［受注停止］Osteoprotegerin (OPG, Tumor Necrosis Factor Receptor Superfamily Member 11B, TNFRSF11B) 10ug 298222
特徴
- Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
- Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro.
- Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B.
- May also play a role in preventing arterial calcification.
- May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis.
- TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:ELISA: 1ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
- Reconstitute with sterile ddH2O.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size：10ug
- Host：goat
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a lyophilized powder in PBS, pH 7.4. No preservative added. Reconstitute with 10ul sterile ddH2O.
- Specificity：Recognizes human Osteoprotegerin.
- Calc Applications Abbrev：E
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to human osteoprotegerin.
- Shelf Life：1year
- Swiss Prot Number：O00300
- EU Commodity Code：30021010
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