Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma.
It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells.
It is closely related to L-arginine, a conditionally-essential amino acid.
ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardiovascular health.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 1:100Optimal dilutions to be determined by the researcher.
Crossreactivity:Using conjugated ADMA-KLH, antibody specificity was performed with an ELISA test by competition experiments with the following compounds:Compound: Cross-reactivity ratio(a):ADMA-BSA: 1SDMA-BSA: 1/>100NDMA-BSA: 1/>100L-Arginine-BSA: 1/>5000
(a) ADMA-BSA concentration/unconjugated or conjugated amino acidsconcentration at half displacementBSA = Bovine Serum Albumin
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with sterile ddH2O.
