L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.
The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/ml.
Recognises a single band migrating at ~103kD Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Thiopropyl Sepharose immunoaffinity chromatography.
Form:Supplied as a liquid in 1% Trehalose, 0.01% sodium azide.
Specificity:Recognizes GluR1 phosphorylated (S845). Species Crossreactivity: Rat.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Rt
Immunogen:Synthetic peptide conjugated to KLH corresponding to aa840-850 of the GluR1 mature chain. Species sequence homology: Mouse, human