Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C.
Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure.
Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.2g/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:sheep
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human Aurora B.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein human His(6)-Aurora B [residues 1-344] expressed in insect cells
Shelf Life:1year
EU Commodity Code:30021010
商品名:Aurora B (AIK2, AIM-1, AIM1, ARK-2, ARK2, AurB, AURKB, AURKB_HUMAN, Aurora 1, Aurora and Ipl1 like midbody Associated Protein 1, Aurora Kinase B, Aurora Related Kinase 2, Aurora- and Ipl1-like midbody-AssociatedProtein 1, Aurora-B, Aurora-Related Kinase 2, Aurora/IPL1 Related Kinase 2, Aurora/IPL1-Related Kinase 2, IPL1, Serine/theronine Kinase 12, Serine/Threonine Protein Kinase 12, Serine/Threonine-Protein Kinase 12, Serine/Threonine-Protein Kinase aurora-B, STK-1, STK1, STK12, STK5) 200ul