LOXL2 is a member of the lysyl oxidase gene family.
This family of extracellular, copper dependent enzymes participates in the post-translational modification essential to the biogenesis of connective tissue by deaminating the side chains of lysine residues in collagen and elastin.
This results in the covalent cross-linking of fibrillar collagen and the formation of desmosine and isodesmosine cross-links in elastin.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Antigen retrieval using heat mediated 10mM citrate buffer, pH 6.0 or Tris-EDTA buffer, pH 8.0 is recommended Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.0, 0.025% Proclin-300, 20% glycerol.
Specificity：Recognizes human LOXL2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to aa454-742 of human LOXL2.
