ESE-1 (for epithelium-specific Ets), is a novel, highly tissue-restricted member of the ets transcription factor:oncogene family, which has features distinct from those of any other ets-related factor.
ESE-1 binds with high affinity to and transactivates the ets binding site in the promoter of the keratinocyte terminal differentiation marker gene, SPRR2A.
ESE-1 is a critical regulator of epithelial cell differentiation.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry(Paraffin): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human ELF3 at N-terminal sequence MAATCEISNIFSNYFS and the C-terminal sequence SSGWKEEEVLQSRN. Species Crossreactivity: monkey
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mk
Immunogen：Synthetic peptide corresponding to human ELF3. Epitope: N-terminal. Species sequence homology: Human, Gorilla, Orangutan, Gibbon, Marmoset, Elephant (100%); Bovine, Canine, Equine, Rabbit (94%); Monkey, Mouse, Rat, Panda, Opossum, Chicken (88%).
