84-2522-65 PLEKHA1 (Pleckstrin Homology Domain-containing Family A Member 1, PH Domain-containing Family A Member 1, TAPP1, Tandem PH Domain-containing Protein 1, TAPP-1) (FITC) 100ul 131451-FITC
84-2522-65 PLEKHA1 (Pleckstrin Homology Domain-containing Family A Member 1, PH Domain-containing Family A Member 1, TAPP1, Tandem PH Domain-containing Protein 1, TAPP-1) (FITC) 100ul 131451-FITC
This gene encodes a pleckstrin homology domain-containing adapter protein.
The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate.
This protein may be involved in the formation of signaling complexes in the plasma membrane.
Polymorphisms in this gene are associated with age-related macular degeneration.
Alternate splicing results in multiple transcript variants.
A pseudogene of this gene is found on chromosome 5.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIKLTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQTVSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Recognizes human PLEKHA1. Species Crossreactivity: mouse.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo
Immunogen:Full length human PLEKHA1, aa1-404 (NP_001001974.1).