84-2479-57 OASIS (Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, cAMP-responsive Element-binding Protein 3-like Protein 1, Old Astrocyte Specifically-induced Substance, Processed Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, CREB3L1, PSEC0238) (Biotin) 100ul 125315-Biotin
84-2479-57 OASIS (Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, cAMP-responsive Element-binding Protein 3-like Protein 1, Old Astrocyte Specifically-induced Substance, Processed Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, CREB3L1, PSEC0238) (Biotin) 100ul 125315-Biotin
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes.
Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity).
May play a role in gliosis.
In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFTENMEDFSNDLFSSFFDDPVLDEKSPLLDMELDSPTPGIQAEHSYSLSGDSAPQSPLVPIKMEDTTQDAEHGAWALGHKLCSIMVKQEQSPELPVDPLAAPSAMAAAAAMATTPLLGLSPLSRLPIPHQAPGEMTQLPVIKAEPLEVNQFLKVTPEDLVQMPPTPPSSHGSDSDGSQSPRSLPPSSPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETFTSENNELWKKVETLENANRTLLQQLQKLQTLVTNKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPEFSSGSQTVKEDPLAADGVYTASQMPSRSLLFYDDGAGLWEDGRSTLLPMEPPDGWEINPGGPAEQRPRDHLQHDHLDSTHETTKYLSEAWPKDGGNGTSPDFSHSKEWFHDRDLGPNTTIKLS
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity:Recognizes human CREB3L1.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Full length human CREB3L1, aa1-519 (NP_443086.1).