This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase.
The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate.
This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration.
Mutations at this locus have been associated with lethal congenital contractural syndrome.
Alternatively spliced transcript variants encoding different isoforms have been described.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MTPRHPLFTSRRPPAQPTRCARKAPAVEKPDPSPRSPARTHTPREQPLHSAQERGRPSSGTGQPRGSQHPSGQAHVGSSLRAQRVCPALGSDLGLSSQPGAHLLAPGIHPSAPALSLRRTPSRHPPGRQGQRSEGVSGTWMASRDRGIVISKAQPPEATPVLPGSPRVALPRALAPETPRACGVTRSSRCGPGRAAPRPGQPPSAE
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity：Recognizes human PIP5K1C.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Full length human PIP5K1C, aa1-206 (AAH11138.1).
