84-2414-10　［取扱停止］Zic1/2/3 (Zinc Finger Protein ZIC 1, Zinc Finger Protein 201, Zinc Finger Protein of the cerebellum 1, ZIC1, ZIC, ZNF201, Zinc Finger Protein ZIC 2, Zinc Finger Protein of the cerebellum 2, ZIC2, Zinc Finger Protein ZIC 3, Zinc Finger Protein 203, Zinc Finger Protein of the cerebellum 3, ZIC3, ZNF203) 100ul　226753

特徴

• Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner.
• Zic is expressed in granule cells that make synaptic contact with Purkinje cells.
• Zic1 is a gene critical to cerebellar pattern formation.
• The expression of Zic genes is first detected at gastrulation and at neurulation, becoming restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm.
• The Zic1 gene has been mapped to chromosome 9 in mouse.
• The 5' flanking region of the Zic1 gene contains a region-specific enhancer determined to be essential in in-vivo and in-vitro deletion analysis.
• The temporal profile of mRNA expression differs for each of the Zic gene products.
• The Drosophila odd-paired gene is highly homologous to the Zic gene family.
• Zic2 and Zic3 are highly similar genes.
• Zic2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation.
• Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.