ZC3H11A (zinc finger CCCH domain-containing protein 11A), also known as KIAA0663 or ZC3HDC11A, is an 810 amino acid protein that contains 3 C3 H1-type zinc fingers.
ZC3H11A is expressed in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, fetal brain and fetal liver.
The gene encoding ZC3H11A maps to human chromosome 1q32.1 and mouse chromosome 1 E4.
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene on chromosome 1 which encodes lamin A.
When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs.
Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of ZC3H11A. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 339-384 of Human ZC3H11A.
