Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression.
ZBTB38 (zinc finger and BTB domain-containing protein 38), also known as CIBZ, is a 1,195 amino acid zinc finger protein that is highly expressed in brain tissue.
Like most other zinc finger proteins, ZBTB38 is thought to function as a transcriptional activator that may specifically influence the differentiation and the survival of late postmitotic neurons.
Additionally,ZBTB38 is a substrate for caspase-3 and may play an important role in the negative regulation of caspase-3-induced apoptosis.
ZBTB38 containsone BTB (POZ) domain and ten C2H2-type zinc fingers, through which it conveys nucleic acid-binding activity.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of ZBTB38. Species Crossreactivity: Human
