84-2413-49　［取扱停止］XRCC5 (X-Ray Repair Cross-Complementing Protein 5, 86kD Subunit of Ku Antigen, ATP-Dependent DNA Helicase 2 Subunit 2, ATP-Dependent DNA Helicase II 80kD Subunit, CTC box-Binding Factor 85kD Subunit, CTC85, CTCBF, DNA Repair Protein XRCC5, Ku80, Ku86, Ku-80, Ku-86, Lupus Ku Autoantigen Protein p86, Nuclear Factor IV, Thyroid-lupus Autoantigen, TLAA, X-Ray Repair C ...　226723

特徴

• XRCC5 encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5.
• Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.
• This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination.
• A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
• Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.