84-2413-39 [取扱停止]XRCC3 (CMM6, DNA Repair Protein XRCC3, RAD51 like, X ray Repair Complementing defective Repair in Chinese hamster, X ray Repair Complementing defective Repair in Chinese hamster Cells 3, X ray Repair cross Complementing Protein 3, X-Ray Repair Cross-Complementing Protein 3, XRCC 3, XRCC3, XRCC3) 100ul 226718
84-2413-39 [取扱停止]XRCC3 (CMM6, DNA Repair Protein XRCC3, RAD51 like, X ray Repair Complementing defective Repair in Chinese hamster, X ray Repair Complementing defective Repair in Chinese hamster Cells 3, X ray Repair cross Complementing Protein 3, X-Ray Repair Cross-Complementing Protein 3, XRCC 3, XRCC3, XRCC3) 100ul 226718
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage.
These genes share sequence similarity with the yeast DNA repair protein Rad51.
XRCC1 is a 70kDa protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks.
XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division.
XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of XRCC3. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to amino acids 41-90 of Human XRCC3.