p53 is a DNA-binding protein that is involved in a variety of processes, including tumor suppression and apoptosis, DNA replication and repair, and cell cycle regulation.
Normal cells and tissues express a low level of p53 under most circumstances, but p53 expression is induced by DNA damage and cellular stress.
Wig-1 (wild type p53-induced gene 1) is a zinc finger protein that contains a putative nuclear localization signal (NLS) and is induced by p53.
Wig-1 expression is increased by whole body gamma irradiation in these tissues as well as in spleen and lung.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of WIG1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human WIG1.
