TXA synthase, also referred to as thromboxane synthase or CYP5, is an enzyme that catalyzes the conversion of the prostaglandin endoperoxide (PGH2) into Thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation.
TXA synthase is an important part of the cytochrome P450 system.
Thromboxane A2 plays a pivotal role in the maintenance of hemostasis and cardiovascular diseases along with Prostacyclin.
The expression of TXA synthase has been found to be consistently upregulated in several types of cancer tissues suggesting the involvement of this enzyme in tumor growth in humans.
Thromboxanes are produced by TXA synthase in excess in inflammatory bowel disease.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of TXA synthase. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to amino acids 427-470 of Human TXA synthase.
Shelf Life：1year
Swiss Prot Number：P24557
EU Commodity Code：30021010
商品名：TXA Synthase (BDPLT14, CYP5, CYP5A1, Cytochrome P450 5A1, Cytochrome P450, Family 5, SubFamily A, Polypeptide 1, FLJ52771, GHOSAL, Platelet cytochrome P450 SubFamily V, TBXAS1, THAS, THAS, Thromboxane A Synthase 1 (platelet), Thromboxane A Synthase 1 (platelet, cytochrome P450, Family 5, SubFamily A), Thromboxane A Synthase 1, Thromboxane A Synthase 1 platelet cytochrome P450 SubFamily V, Thromboxane-A Synthase, TS, TXA Synthase, TXAS, TXS) 100ul
